Participation in a large number of clinical studies on drug-coated balloon catheters (PAD), leg vein thrombosis and pulmonary embolism. Initiation and implementation of basic research projects. PD Dr. P. Kuhlencordt was funded by the German Research Foundation, the Interdisciplinary Center for Clinical Research (IZKF Würzburg), MSD Sharp & Dohme GmbH, Bayer Vital and Hoffmann-La Roche.

• 2000 New Investigator Award; American Heart Association
• 2003 Young Investigator Award; 19th Cardiologists/Physiologists Workshop Coronary Dysfunction, Dresden
• 2003 First Poster Prize; Conference Medical Clinic University of Würzburg, Bad Brückenau
• 2004 Young Investigator Award; 20th Cardiologists/Physiologists Workshop Coronary Dysfunction, Bern
• 2006 Max Ratschow Prize; German Society for Angiology
• FOCUS Top doctors for leg vessels/pAVK 2018
• FOCUS Top doctors for leg vessels/pAVK 2019

• Member of the Advisory Board of the German Society of Angiology (DGA), member of the Research and Teaching Commission
• Founding member of the "Young Angiologists" forum of the DGA
• Head of the project group "National Competence-Based Learning Objectives Catalog Medicine (NKLM)" of the German Society of Angiology
• Member of the Angiology Program Commission for the DGIM Annual Meetings 2017-2020
• Member of the Hamburg Society for Diabetes
• Member of the German Society for Angiology
• Member of the German Society of Cardiology
• Member of the German Society for Internal Medicine
• Member of the European Society of Cardiology

Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease.

HPS3/TIMI55-REVEAL Collaborative Group, Bowman L, Hopewell JC, Chen F, Wallendszus K, Stevens W, Collins R, Wiviott SD, Cannon CP, Braunwald E, Sammons E, Landray MJ.

N Engl J Med. 2017 Sep 28;377(13):1217-1227. doi: 10.1056/NEJMoa1706444. Epub 2017 Aug 28.

[Treatment and Secondary Prevention of Venous Thromboembolism - Change in Oral Anticoagulation].

Helms TM, Gulba D, Ahrens I, Schäfer A, Hankowitz J, 

Kuhlencordt P

Lipp HP, Nikol S, Riess H, Stargardt T, Bramlage P.

Dtsch Med Wochenschr. 2017 Jul;142(13):986-993. doi: 10.1055/s-0042-124132. Epub 2017 Apr 19. Review. German. 

Ultrasound Assisted Endovascular Thrombolysis in Adolescents: 2 Case Reports.

Olivieri M, Kurnik K, Hoffmann F, Reiter K, Bidlingmaier C, 

Kuhlencordt P

, Treitl M.

Pediatrics. 2016 Jul;138(1). pii: e20160022. doi: 10.1542/peds.2016-0022. epub 2016 Jun 9.

Hypothenar hammer syndrome.

Schröttle A, Czihal M, Lottspeich C, 

Kuhlencordt P

, Nowak D, Hoffmann U.

Vasa. 2015 May;44(3):179-85. doi: 10.1024/0301-1526/a000427. Review.

Impact of cranial and axillary/subclavian artery involvement by color duplex sonography on response to treatment in giant cell arteritis.

Czihal M, Piller A, Schroettle A, 

Kuhlencordt P

, Bernau C, Schulze-Koops H, Hoffmann U.

J Vasc Surg. 2015 May;61(5):1285-91. doi: 10.1016/j.jvs.2014.12.045. Epub 2015 Feb 3.

Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis.

Hellfritsch J, Kirsch J, Schneider M, Fluege T, Wortmann M, Frijhoff J, Dagnell M, Fey T, Esposito I, Kölle P, Pogoda K, Angeli JP, Ingold I, 

Kuhlencordt P

Östman A, Pohl U, Conrad M, Beck H.

Antioxid Redox Signal. 2015 Apr 10;22(11):938-50. doi: 10.1089/ars.2014.5889.

Images in Vascular Medicine. Painful nodule of the forehead after blunt trauma: superficial temporal artery pseudoaneurysm.

Czihal M, Sturm A, Hoffmann U,

Kuhlencordt PJ

Vasc Med. 2015 Feb;20(1):86-7. doi: 10.1177/1358863X14564497. Epub 2015 Jan 13. No abstract available. 

Niacin reverses migratory macrophage foam cell arrest mediated by oxLDL in vitro.

Huang H, Koelle P, Fendler M, Schroettle A, Czihal M, Hoffmann U,

Kuhlencordt PJ

PLoS One. 2014 Dec 18;9(12):e114643. doi: 10.1371/journal.pone.0114643. eCollection 2014.

Clinical characteristics and course of plantar vein thrombosis: a series of 22 cases.

Czihal M, Röling J, Rademacher A, Schröttle A, 

Kuhlencordt P

, Hoffmann U.

Phlebology. 2015 Dec;30(10):714-8. doi: 10.1177/0268355514555385. Epub 2014 Oct 17.

Induction of inducible nitric oxide synthase (iNOS) expression by oxLDL inhibits macrophage derived foam cell migration.

Huang H, Koelle P, Fendler M, Schröttle A, Czihal M, Hoffmann U, Conrad M,

Kuhlencordt PJ

. Atherosclerosis. 2014 Jul;235(1):213-22. doi: 10.1016/j.atherosclerosis.2014.04.020. Epub 2014 May 10.

Combined deficiency in glutathione peroxidase 4 and vitamin E causes multiorgan thrombus formation and early death in mice.

Wortmann M, Schneider M, Pircher J, Hellfritsch J, Aichler M, Vegi N, Kölle P, 

Kuhlencordt P

Walch A, Pohl U, Bornkamm GW, Conrad M, Beck H.

Circ Res. 2013 Aug 2;113(4):408-17. doi: 10.1161/CIRCRESAHA.113.279984. Epub 2013 Jun 14.

Juvenile temporal arteritis.

Czihal M, Tatò F, Hoffmann U,

Kuhlencordt PJ

Clin Exp Rheumatol. 2013 Jan-Feb;31(1 Suppl 75):S89. Epub 2012 Dec 6. No abstract available. 

Outcome of giant cell arteritis of the arm arteries managed with medical treatment alone: cross-sectional follow-up study.

Czihal M, Piller A, Schroettle A,

Kuhlencordt PJ

Schulze-Koops H, Hoffmann U.

Rheumatology (Oxford). 2013 Feb;52(2):282-6. doi: 10.1093/rheumatology/kes239. Epub 2012 Sep 16.

Oral rivaroxaban for the treatment of symptomatic pulmonary embolism.

EINSTEIN-PE Investigators, Büller HR, Prins MH, Lensin AW, Decousus H, Jacobson BF, Minar E, Chlumsky J, Verhamme P, Wells P, Agnelli G, Cohen A, Berkowitz SD, Bounameaux H, Davidson BL, Misselwitz F, Gallus AS, Raskob GE, Schellong S, Segers A.

N Engl J Med. 2012 Apr 5;366(14):1287-97. doi: 10.1056/NEJMoa1113572. Epub 2012 Mar 26.

Sonographic and clinical pattern of extracranial and cranial giant cell arteritis.

Czihal M, Zanker S, Rademacher A, Tatò F,

Kuhlencordt PJ

Schulze-Koops H, Hoffmann U.

Scand J Rheumatol. 2012 May;41(3):231-6. doi: 10.3109/03009742.2011.641581. Epub 2012 Mar 9.

eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice.

Ponnuswamy P, Schröttle A, Ostermeier E, Grüner S, Huang PL, Ertl G, Hoffmann U, Nieswandt B,

Kuhlencordt PJ

PLoS One. 2012;7(1):e30193. doi: 10.1371/journal.pone.0030193. Epub 2012 Jan 23.

Involvement of the femoropopliteal arteries in giant cell arteritis: clinical and color duplex sonography.

Czihal M, Tatò F, Rademacher A, 

Kuhlencordt P

Schulze-Koops H, Hoffmann U.

J Rheumatol. 2012 Feb;39(2):314-21. doi: 10.3899/jrheum.110566. Epub 2012 Jan 15.

[Recent advances in the treatment of superficial vein thrombosis and extracranial carotid artery stenosis].

Bauersachs RM,

Kuhlencordt PJ

Dtsch Med Wochenschr. 2011 Feb;136(5):168-71. doi: 10.1055/s-0031-1272501. Epub 2011 Jan 26. review. German. 

Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation.

Mandal PK, Schneider M, Kölle P, 

Kuhlencordt P

Förster H, Beck H, Bornkamm GW, Conrad M.

Cancer Res. 2010 Nov 15;70(22):9505-14. doi: 10.1158/0008-5472.CAN-10-1509. Epub 2010 Nov 2.

System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency.

Mandal PK, Seiler A, Perisic T, Kölle P, Banjac Canak A, Förster H, Weiss N, Kremmer E, Lieberman MW, Bannai S, 

Kuhlencordt P

, Sato H, Bornkamm GW, Conrad M.

J Biol Chem. 2010 Jul 16;285(29):22244-53. doi: 10.1074/jbc.M110.121327. Epub 2010 May 12.

[Cerebrovascular diseases].

Kuhlencordt PJ

, Röling J, Hoffmann U.

Internist (Berl). 2009 Aug;50(8):945-51. doi: 10.1007/s00108-009-2367-1. Review. German. 

Oxidative stress and compartment of gene expression determine proatherosclerotic effects of inducible nitric oxide synthase.

Ponnuswamy P, Ostermeier E, Schröttle A, Chen J, Huang PL, Ertl G, Nieswandt B,

Kuhlencordt PJ

Am J Pathol. 2009 Jun;174(6):2400-10. doi: 10.2353/ajpath.2009.080730.

Expression of neuronal nitric oxide synthase splice variants in atherosclerotic plaques of apoE knockout mice.

Schödel J, Padmapriya P, Marx A, Huang PL, Ertl G,

Kuhlencordt PJ

Atherosclerosis. 2009 Oct;206(2):383-9. doi: 10.1016/j.atherosclerosis.2009.02.033. Epub 2009 Mar 14.

Overlapping and distinct roles for PI3Kbeta and gamma isoforms in S1P-induced migration of human and mouse endothelial cells.

Heller R, Chang Q, Ehrlich G, Hsieh SN, Schoenwaelder SM,

Kuhlencordt PJ

Preissner KT, Hirsch E, Wetzker R.

Cardiovasc Res. 2008 Oct 1;80(1):96-105. doi: 10.1093/cvr/cvn159. Epub 2008 Jun 16.

NO-synthase-/NO-independent regulation of human and murine platelet soluble guanylyl cyclase activity.

Gambaryan S, Kobsar A, Hartmann S, Birschmann I,

Kuhlencordt PJ

, Müller-Esterl W, Lohmann SM, Walter U.

J Thromb Haemost. 2008 Aug;6(8):1376-84. doi: 10.1111/j.1538-7836.2008.03014.x. Epub 2008 May 14.

Ezetimibe potently reduces vascular inflammation and arteriosclerosis in eNOS-deficient ApoE ko mice.

Kuhlencordt PJ

Padmapriya P, Rützel S, Schödel J, Hu K, Schäfer A, Huang PL, Ertl G, Bauersachs J.

Atherosclerosis. 2009 Jan;202(1):48-57. doi: 10.1016/j.atherosclerosis.2008.03.021. Epub 2008 Apr 6.

The heart communicates with the endothelium through the guanylyl cyclase-A receptor: acute handling of intravascular volume in response to volume expansion.

Schreier B, Börner S, Völker K, Gambaryan S, Schäfer SC, 

Kuhlencordt P

, Gassner B, Kuhn M.

Endocrinology. 2008 Aug;149(8):4193-9. doi: 10.1210/en.2008-0212. Epub 2008 May 1.

Large external iliac vein aneurysm in a patient with a post-traumatic femoral arteriovenous fistula.

Kuhlencordt PJ

Linsenmeyer U, Rademacher A, Sadeghi-Azandaryani M, Steckmeier B, Hoffmann U.

J Vasc Surg. 2008 Jan;47(1):205-8. doi: 10.1016/j.jvs.2007.07.060.

Native C-reactive protein induces endothelial dysfunction in ApoE-/- mice: implications for iNOS and reactive oxygen species.

Schwedler SB,

Kuhlencordt PJ

Ponnuswamy PP, Hatiboglu G, Quaschning T, Widder J, Wanner C, Potempa LA, Galle J.

Atherosclerosis. 2007 Dec;195(2):e76-84. epub 2007 Jul 31.

Tissue-specific effects of the nuclear factor kappaB subunit p50 on myocardial ischemia-reperfusion injury.

Frantz S, Tillmanns J,

Kuhlencordt PJ

Schmidt I, Adamek A, Dienesch C, Thum T, Gerondakis S, Ertl G, Bauersachs J.

Am J Pathol. 2007 Aug;171(2):507-12. epub 2007 Jun 7.

Atheroprotective effects of neuronal nitric oxide synthase in apolipoprotein e knockout mice.

Kuhlencordt PJ

Hötten S, Schödel J, Rützel S, Hu K, Widder J, Marx A, Huang PL, Ertl G.

Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1539-44. epub 2006 Apr 20.

Myocardial contractile efficiency increases in proportion to a fetal enzyme shift in chronically infarcted rat hearts.

Naumann A, Neubauer S, 

Kuhlencordt P

, Hu K, Tian R, Gaudron P, Ertl G.

Basic Res Cardiol. 2005 Mar;100(2):171-8. Epub 2005 Feb 3.

Integrin-linked kinase regulates endothelial cell survival and vascular development.

Friedrich EB, Liu E, Sinha S, Cook S, Milstone DS, MacRae CA, Mariotti M,

Kuhlencordt PJ

Force T, Rosenzweig A, St-Arnaud R, Dedhar S, Gerszten RE.

Mol Cell Biol. 2004 Sep;24(18):8134-44.

Role of endothelial nitric oxide synthase in endothelial activation: insights from eNOS knockout endothelial cells.

Kuhlencordt PJ

Rosel E, Gerszten RE, Morales-Ruiz M, Dombkowski D, Atkinson WJ, Han F, Preffer F, Rosenzweig A, Sessa WC, Gimbrone MA Jr, Ertl G, Huang PL.

Am J Physiol Cell Physiol. 2004 May;286(5):C1195-202. epub 2004 Jan 28.

Increased myocardial oxygen consumption by TNF-alpha is mediated by a sphingosine signaling pathway.

Hofmann U, Domeier E, Frantz S, Laser M, Weckler B, 

Kuhlencordt P

Heuer S, Keweloh B, Ertl G, Bonz AW.

Am J Physiol Heart Circ Physiol. 2003 Jun;284(6):H2100-5. Epub 2003 Jan 30.

Effects of chronic treatment with L-arginine on atherosclerosis in apoE knockout and apoE/inducible NO synthase double-knockout mice.

Chen J, 

Kuhlencordt P

Urano F, Ichinose H, Astern J, Huang PL.

Arterioscler Thromb Vasc Biol. 2003 Jan 1;23(1):97-103.

Hypertension does not account for the accelerated atherosclerosis and development of aneurysms in male apolipoprotein e/endothelial nitric oxide synthase double knockout mice.

Chen J,

Kuhlencordt PJ

, Astern J, Gyurko R, Huang PL.

Circulation. 2001 Nov 13;104(20):2391-4.

Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice.

Kuhlencordt PJ

Gyurko R, Han F, Scherrer-Crosbie M, Aretz TH, Hajjar R, Picard MH, Huang PL.

Circulation. 2001 Jul 24;104(4):448-54.

Genetic deficiency of inducible nitric oxide synthase reduces atherosclerosis and lowers plasma lipid peroxides in apolipoprotein E-knockout mice.

Kuhlencordt PJ

Chen J, Han F, Astern J, Huang PL.

Circulation. 2001 Jun 26;103(25):3099-104.

Modulation of mouse cardiac function in vivo by eNOS and ANP.

Gyurko R, 

Kuhlencordt P

Fishman MC, Huang PL.

Am J Physiol Heart Circ Physiol. 2000 Mar;278(3):H971-81.

Book contributions:

1. Kuhlencordt, P.Schroettle, A.: Diseases of the heart; H. Wagner, M. Fischereder (eds.): Internal medicine for dentists. Georg Thieme Verlag 2012. ISBN 978-3-13-103482-3.
2. Schroettle, A., Kuhlencordt, P.: Diseases of the circulatory and vascular system; H. Wagner, M. Fischereder (eds.): Innere Medizin für Zahnmediziner. Georg Thieme Verlag 2012. ISBN 978-3-13-103482-3.
3. Kuhlencordt, P. J.: Vascular examination methods, non-apparative diagnostics; E. S. Debus, W. Gross-Fengels (eds.): Operative and interventional vascular medicine. Springer Verlag 2012. ISBN 978-3-642-01709-4. (New edition in preparation)
4. Bley, Th., Kuhlencordt, P. J.: Vascular examination methods, imaging diagnostics; E. S. Debus, W. Gross-Fengels (eds.): Operative and interventional vascular medicine. Springer Verlag 2012. ISBN 978-3-642-01709-4. (New edition in preparation)
5. Müller, J. G., Kuhlencordt, P.: Arteriosclerosis; E. S. Debus, W. Gross-Fengels (Eds.): Operative and interventional vascular medicine. Springer Verlag 2012. ISBN 978-3-642-01709-4. (New edition in preparation)
6. Amman-Vesti, B., Fontana, A., Kuhlencordt, P.Müller, J. G.: Vasculitides. E. S. Debus, W. Gross-Fengels (Eds.): Operative and interventional vascular medicine. Springer Verlag 2012. ISBN 978-3-642-01709-4 (new edition in preparation)
7. Kuhlencordt, P. J.: Abdominal aorta; H. Lehnert (ed.): DGIM Innere Medizin. SpringerReference Live, Springer Verlag 2015 (online).